Construção de um plano terapêutico multiprofissional para cuidados de pacientes em internação hospitalar / Construction of a multiprofessional therapeutic plan for the care of hospitalized patients / Construcción de un plan terapéutico multiprofesional para el cuidado de pacientes hospitalizados

INTRODUÇÃO: O Plano Terapêutico, trata-se de um plano de cuidado voltado para cada paciente, considerando sua individualidade e integralidade. O impulso a abordar essa temática se deu a partir da aproximação com um dos campos de atuação, enquanto residente em Urgência e Emergência. OBJETIVO: Construir um plano terapêutico multiprofissional para cuidados de pacientes em internação hospitalar. METODOLOGIA: Estudo metodológico, com abordagem quantitativa, desenvolvido em duas etapas: 1) Realização de revisão integrativa sobre a temática de interesse; 2) Elaboração da tecnologia, com suporte de designer gráfico, realizado entre os meses de novembro 2022 a janeiro de 2023. RESULTADOS: Construiu-se o plano terapêutico, contendo seis domínios, compostos por 27 itens. Os itens trazem, os dados pessoais do paciente, ,antecedentes pessoais, medicações contínuas, descrição do plano articulado pela equipe multiprofissional, descrição de possíveis novos terapêutivos e feedback da equipe. CONCLUSÃO: Esse instrumento de trabalho fortalece a troca de saberes das múltiplas especialidades envolvidas no cuidado, além da assistência integral ao paciente.

INTRODUCTION: The Therapeutic Plan is a care plan aimed at each patient, considering their individuality and completeness. The impetus to approach this theme came from the approach with one of the fields of action, while residing in Urgência e Emergência. OBJECTIVE: To build a multidisciplinary therapeutic plan for the care of hospitalized patients. METHODOLOGY: Methodological study, with a quantitative approach, developed in two stages: 1) Conducting an integrative review on the topic of interest; 2) Elaboration of the technology, with the support of a graphic designer, carried out between the months of November 2022 to January 2023. RESULTS: The therapeutic plan was constructed, containing six domains, composed of 27 items. The items bring the patient's personal data, personal history, continuous medications, description of the plan articulated by the multidisciplinary team, description of possible new therapies and team feedback. CONCLUSION: This work instrument strengthens the exchange of knowledge of the multiple specialties involved in care, in addition to comprehensive patient care.

INTRODUCCIÓN: El Plan Terapéutico es un plan de cuidados dirigido a cada paciente, considerando su individualidad e integralidad. El impulso para abordar este tema surgió del acercamiento con uno de los campos de actuación, durante la residencia en Urgência e Emergência. OBJETIVO: Construir un plan terapéutico multidisciplinar para el cuidado de pacientes hospitalizados. METODOLOGÍA: Estudio metodológico, con abordaje cuantitativo, desarrollado en dos etapas: 1) Realización de una revisión integradora sobre el tema de interés; 2) Elaboración de la tecnología, con el apoyo de un diseñador gráfico, realizada entre los meses de noviembre de 2022 a enero de 2023. RESULTADOS: Se construyó el plan terapéutico, que contiene seis dominios, compuestos por 27 ítems. Los ítems traen los datos personales del paciente, historia personal, medicaciones continuas, descripción del plan articulado por el equipo multidisciplinar, descripción de posibles nuevas terapias y feedback del equipo. CONCLUSIÓN: Este instrumento de trabajo refuerza el intercambio de conocimientos de las múltiples especialidades implicadas en la asistencia, además de la atención integral al paciente.

Cashew apple fiber prevents high fat diet-induced obesity in mice: an NMR metabolomic evaluation.

Dietary fiber intake plays an important role in the prevention of obesity. This study aimed at investigating the effect of cashew fiber without low molecular weight compounds (CABwc) on obesity prevention and metabolomics in a murine model of diet-induced obesity. Mice were fed a chow diet (CD), a high-fat diet (HFD) or a high-fat diet supplemented with CABwc (10%) (HFD-CABwc) for 15 weeks. The body weight, abdominal fat, serum glucose levels, insulin and lipid profiles, satiety hormones such as leptin and ghrelin, digestive enzymes such as amylase and lipase, and inflammatory mediators such as TNF-α, IL-6, and adiponectin were measured, in addition to performing serum and hepatic tissue analyses. The metabolomic analysis was based on nuclear magnetic resonance (NMR) spectroscopy of serum and feces. The effects observed with ingestion of CABwc were appetite control and prevention of hyperglycemia, hyperinsulinemia and hypertriglyceridemia, as well as the prevention of the inflammatory process and reduction of liver injury caused by the HFD. In addition, NMR evidenced the presence of SCFAs in serum and feces of mice fed with HFD-CABwc. These findings suggest that CABwc promoted satiety in mice, improving the metabolism of glucose and lipids. Positive effects of obesity prevention may be associated with SCFA production.

Antidepressant-Like Effect of Lippia sidoides CHAM (Verbenaceae) Essential Oil and Its Major Compound Thymol in Mice.

Depression is a common disease affecting more than 300 million people worldwide. Since Lippia sidoides has shown central nervous system effects in previous works, we aimed to investigate the effect of L. sidoides essential oil and its major compound, thymol on a corticosterone-induced depression model in mice. Male mice (20⁻25 g) received corticosterone (20 mg/kg, subcutaneously), once a day for 22 days. From the 16th day on, mice were grouped to receive either corticosterone or L. sidoides essential oil (100 and 200 mg/kg), or thymol (25 and 50 mg/kg) or fluoxetine (35 mg/kg) by gavage. The forced swimming test, tail suspension, open field, elevated plus maze and sucrose preference tests were performed from the 19th to 22nd day. Data were analyzed by ANOVA followed by the Student-Newman-Keuls as a post hoc test and the results were considered significant when p < 0.05. It was shown that L. sidoides essential oil, thymol and fluoxetine decreased the immobility time in the tail suspension and forced swimming tests and none of these altered locomotor activity in the open field test. However, the drugs increased the amount of grooming. In the elevated plus maze, all drugs increased the number of entries and the time of permanence in the open arms. In the sucrose preference test, the L. sidoides essential oil, thymol and fluoxetine reversed anhedonia. These results suggest that the thymol and L. sidoides essential oil have an antidepressant-like effect, similar to fluoxetine. However, future studies should be encouraged to enhance understanding of the effects of essential oil and thymol for the treatment of depression.